'Mass Entrepreneurship, mass innovation' provides an important time opportunity for higher vocational colleges to train new technology application talents, which is also a concrete action for higher vocational colleges to carry out the strategy of 'Dual entrepreneurship'. The training of new technology application talents in higher vocational colleges focuses on training students to become new technology application talents with the characteristics of entrepreneurs. In the course of practice, we have accumulated the following concrete experiences, namely, expanding the scope of production to cultivate innovative and entrepreneurial talents, strengthening the education of innovation and entrepreneurship by learning, deepening the research to enhance the ability of innovation and entrepreneurship, and improving the degree of innovation and entrepreneurship by creating, create a high ground for innovation and entrepreneurship. Reflect on the existing practice, it is urgent to introduce new technology into the curriculum of higher vocational education, to promote the main body consciousness of enterprises participating in training new technology application talents, and to improve the ability of new technology service enterprises in higher vocational colleges.