Ti-5Nb-xFe三元合金於牙科應用性質之研究

A study on the properties of the ternary Ti-5Nb-xFe alloys for dental applications

陳佳姿(Chia-Tzu Chen)

指導教授 ： 吳世經 ； 許學全

中臺科技大學/健康科學院/醫學工程暨材料研究所/碩士(2010年)

摘要

本研究選用新熔製的三元Ti-5Nb-xFe (x=1、2、3、4、5) 合金為基材，並與c.p. Ti及Ti-6Al-4V合金作比較，進行人工唾液的耐蝕性、生物相容性分析和陶瓷燒附強度 (Duceratin)，透過一系列Ti-5Nb-xFe合金之測試評估以了解在牙科應用之可行性。極化曲線結果顯示，Ti-5Nb-xFe合金、c.p. Ti和Ti-6Al-4V在不同酸鹼值裡 (pH = 4、5和6) 其腐蝕行為是相似的，另一方面，在含氟的人工唾液中，Ti-5Nb-xFe合金之耐蝕性也優於c.p. Ti和Ti-6Al-4V合金。掃描電子顯微鏡觀察和細胞活性分析顯示，纖維母細胞（L929）的生長對所有的Ti-5Nb-xFe合金、c.p. Ti和Ti-6Al-4V合金具有良好的生物相容性。陶瓷燒附強度方面顯示，Ti-5Nb-xFe合金結合強度方面皆高於ISO9693標準 (25 MPa)，以Ti-5Nb-5Fe有最高結合強度 (31.3 MPa)，並高於c.p. Ti (30.4 MPa) 和 Ti-6Al-4V (23.3 MPa)合金。與金屬表面陶瓷殘留量相比可知，c.p. Ti和Ti-6Al-4V陶瓷殘留量較少，而在Ti-5Nb-5Fe合金觀察到較多的陶瓷殘留量。

關鍵字

鈦合金 ； 人工唾液 ； 耐蝕性 ； 生物相容性 ； 結合強度

並列摘要

This research aims to evaluate the ternary Ti-5Nb-xFe (x =1, 2, 3, 4 and 5) alloys, compared with that of commercially pure titanium (c.p. Ti) and the Ti-6Al-4V alloy. These evaluations include the bond strengths between porcelain (Duceratin), their corrosion resistance against artificial saliva, and their biocompatibility. Through this evaluation criterion, the applicability of Ti-5Nb-xFe alloys in the dental field can be more intimately understood.Linear polarization results showed that artificial saliva combined with various pH levels (pH = 4, 5 and 6) resulted in similar corrosion behavior in Ti-5Nb-xFe alloys, c.p. Ti and the Ti-6Al-4V alloy. On the other hand, Ti-5Nb-xFe alloys had better resistance to corrosion in the fluoride-containing artificial saliva than that of c.p. Ti and the Ti-6Al-4V alloy.SEM observation and MTT assay indicate that the fibroblast cell (L929) growth on all Ti-5Nb-xFe alloys,c.p. Ti and the Ti-6Al-4V alloy showed good biocompatibility.These results indicate that Ti-5Nb-5Fe alloy had the highest bond strength (31.3 MPa), which was higher than that of c.p. Ti (30.4 MPa) and the Ti-6Al-4V alloy (23.3 MPa).The bond strengths of all the Ti-5Nb-xFe alloys exceeded the lower limit value in the ISO9693 standard for the 3-point bending test (25 MPa). By contrast, the surface of c.p. Ti and the Ti-6Al-4V alloy after de-bonding exhibited the least amount of retained porcelain on the metal surface, and a higher rate of adhesive bond failure. More traces of retained porcelain were observed on Ti-5Nb-xFe alloys, such as the Ti-5Nb-5Fe alloy.

並列關鍵字

Biocompatibility ； Bond Strength ； Artificial Saliva ； Titanium Alloy ； Corrosion Resistance

參考文獻

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