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下顎骨中心性巨細胞肉芽腫-病例報告

Central Giant Cell Granuloma of the Jaw-A Case Report

摘要


顎骨中心性巨細胞肉芽腫為一罕見、良性而且出現在顎骨區的非腫瘤性病變,病因目前並不明確。顎骨中心性巨細胞肉芽腫的發生率大約為0.0001%,患病的年齡層很廣,從2歲至80歲都可能出現,但有60%的病人患病年齡在30歲前。病灶通常出現下顎前區,且在大多數病人為無症狀而是在例行的牙科放射線檢查時被發現的。本篇文章中我們提出一位23歲男性因持續數天的右臉腫脹以及間歇性疼痛就診。切片檢查之病理學初步診斷為巨細胞病變,並懷疑是中心性巨細胞肉芽腫。經手術摘除術合併刮除術後,病理學診斷證實為中心性巨細胞肉芽腫。病人術後持續定期回門診追蹤且無復發跡象。本文提出此病例報告並回顧當前文獻。

並列摘要


Central giant cell granuloma is an uncommon, benign, and non-neoplastic lesion of the jaw with an unknown etiology. The incidence of central giant cell granuloma in the general population is 0.0001%. Central giant cell granulomas may be suffered in patients from 2 to 80 year-old and 60% of all cases occur before 30 year-old. The lesions are more common in the anterior mandible. Most cases of central giant cell granulomas are asymptomatic and are found during routine dental x-ray examination. Here we report a case of 23-year-old man who suffered a right facial intermittent dull pain and swelling for days. The pathological report of an incisional biopsy revealed giant cell lesion, and a central giant cell granuloma was suspected. The surgery of enucleation with curettage under general anesthesia was done and the pathological report revealed central giant cell granuloma. Postoperative follow-up was arranged in out-patient department and there was no recurrence of the lesion. Review of literature was also performed.

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