The system and processes of center of fleet management (CFM) has a unseparately relationship with the aircraft availability rate. Recent years, scholars used Information Systems Management and Knowledge Management analysis concepts to improve the management process of CFM. This study will introduce the System Engineering Management which is developed by U.S. government, Department of Defense and private vendors. After that, this study would introduce the process and challenges of main duty of CFM: maintenance control and annual plan preparation of materiel processes; Finally, the systems engineering management concept into the CFM control process. Base on the customer needs and satisfaction as the goal to improve the efficiency of management of maintenance and the reliable of annual plan preparation of materiel processes.