Rice flour was used to study the effects of process variables on extrudate's physical properties in an APV Baker MPF50/25 twin-screw extruder. The process variables were screw profile, feed rate, and screw speed. The extrudate's physical properties measured in this study were true density, bulk density, apparent specific volume, and breaking strength. The effects of the process variables on the physical properties were investigated. The feed rate was the most important variable affecting the extrudate's physical properties. Screw speed was the second important factor affecting the physical properties of the extrudate. The screw profile affected the extrudate's physical properties least.