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鼻中隔多型性腺瘤併反覆性鼻出血

Pleomorphic Adenoma of the Nasal Septum with Recurrent Epistaxis

摘要


多型性腺瘤又稱混合性瘤,是唾液腺組織中常見的良性腫瘤,主要見於大唾液腺,特別是腮腺,其次是下頷腺及小唾液腺,然而發生於咽、喉、氣管、淚腺及鼻腔的多型性腺瘤則相當少見。本科於2008年4月經歷1病例,患者爲58歲女性,主訴右側反覆性鼻出血及鼻塞,持續約有半年,經切除後病理報告爲多型性腺瘤,術後門診追蹤至今情況良好,無復發跡象。鼻腔內多型性腺瘤大都發生於鼻中隔,臨床表徵常見爲單側性鼻塞及鼻出血,其它症狀尚有鼻內異物感、腫脹感,淚漏、頭痛和問斷化膿黏液性鼻漏產生。因生長緩慢,多於症狀明顯產生後才發現,在臨床上容易錯誤診斷爲鼻息肉或肉茅組織腫瘤。

並列摘要


Pleomorphic adenoma, which is also called mixed tumor is frequently observed in the salivary glands. It is considered to occur primarily in the major salivary gland such as parotid gland. The other sites of origin are submandibular gland and minor salivary glands. More uncommon sites are the upper aerodigestive tract including the pharynx, larynx, trachea, lacrimal glands and nasal cavity. A 58-years-old female patient presented with frequent epistaxis and progressive nasal stuffiness over right side for half one year. After excised, the histopathological report revealed a pleomorphic adenoma. She has been followed for more than one year regularly without evidence of recurrence until now. The most common origin site of intranasal pleomorphic adenoma is the nasal septum. Patients commonly present with monolateral nasal obstruction and epistaxis. Other symptoms include a mass in the nose, nasal swelling, epiphora, headache and intermittent mucopurulent rhinorrhoea. Due to slow-growing, clinical symptoms appear after a long silent period and intranasal pleomorphic adenoma may be misdiagnosed to consider nasal polyps or granuloma.

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