Purposes: The purposes of the study were to understand the behavioral intention of smoking cessation, and also explored the relationship between the behavioral intention and influential factors including personal, family, and school factors. Eight senior and vocational high schools in Taipei City and New Taipei City (Taipei County) participating the study.Methods: The data was collected by using cross-sectional investigative study. A total of 130 tenth and eleventh grade smoking students completed self-administrated questionnaires. The respondent rate was 100%.Results: The students who had shorter smoking years, smoked less than 100 cigarettes, had low level nicotine dependence, had positive attitude, and had higher self-efficacy of smoking cessation (individual factors), who were in single-parent family (family factors), and who were in lower grade, and had half or less than half of good friends who were smokers (school factors), were more likely to have short-term (one month) smoking cessation intention. The students who had shorter smoking years, had low level nicotine dependence, had positive attitude to smoking cessation (individual factors), who disagreed with smoking behavior of adolescents by parents and relatives who lived together (family factors), who were lower grade, had half or less than half good friends who were smokers, and disagreed with smoking behaviors of adolescents by good friends (school factors), were more likely to have long-term (six months) smoking cessation intention.Suggestions: The study suggests that the high schools should help smoking adolescents to develop refusal skills of smoking, and to strengthen their motivation of smoking cessation.