With rapid development of software tools and applications, expertises in sport and exercise science have to understand statistical methods and applications as well as the improvement trend. First, this review introduced the applications in the sport and exercise science in the time series context, multi-level context, and methodological context. Second, this review presented an example of a latent growth model analysis, which has been widely used in longitudinal research, to introduce how to fit the model in the sport and exercise science. Finally, this review concluded some important viewpoints when conducting a quantitative study. In sum, this review tried to help researchers get more understanding in statistical analysis methods, integrate statistical analysis application, and enhance theory development in sport and exercise science.