Neurofibroma in the Left Mandible: A Case Report

Translated Titles



陶謙(Qian Tao);王一(Yi Wang);鄭超群(Chao-Qun Zheng)

Key Words

診斷 ; 下頜骨 ; 神經纖維瘤 ; diagnosis ; mandible ; neurofibroma


The Kaohsiung Journal of Medical Sciences

Volume or Term/Year and Month of Publication

26卷4期(2010 / 04 / 01)

Page #

217 - 221

Content Language


Chinese Abstract


English Abstract

We report a rare case of isolated neurofibroma arising in the left mandible without family history of neurofibromatosis type 1. The tumor was histopathologically analyzed and an immunohistochemical panel comprising S-100 protein was performed. Vim, HMB45, and HHF35 were negative. The tumor cells were fusiform in shape, arranged in a plexiform manner, and grew actively. Features typical of neurofibroma, including an enlarged nerve fascicle composed of elongated nuclei and scant cytoplasmic cells, were identified. Our study suggest that neurofibroma can occur in the jaw as an isolated benign tumor in patients without other features of neurofibromatosis type 1.

Topic Category 醫藥衛生 > 醫藥衛生綜合