背景:本研究之目的是探討鹽攝取量與尿鹽排出量之相關性,並檢查用來測量24小時尿鹽排出的自我監測裝置之校度。方法:12位健康的年輕女性自願者,攝取14天的實驗餐並藉由自我監測裝置來測量其第2天到第15天的尿鹽排出量。實驗餐中所含的鹽量分別如下:10克(第1到5天)、6克(第6到8天)、13克(第9到11天)、6克(第12天)、13克(第13天)、及6克(第14天)。結果:由隔夜的尿液樣本中,24小時平均尿鹽排出量分別為:第2到6天為8.01克、第7到9天為5.86克、第10到12天為9.69克、第13天為6.51克、第14天為8.60克、第15天為6.28克。因此,在高鹽攝取期,排出鹽量與(前一日)鹽攝取量之比值約為0.8;在低鹽攝取期比值為1.0。結論:在這些健康的年輕女性族群中,藉由使用自我監測裝置來測量24小時尿鹽排出量,對於偵測每日鹽攝取的改變是一項合理且有效的方法。
Background: The purpose of this study was to investigate the relationship between salt intake and urinary salt excretion and to examine the validity of a self-monitoring device for estimating 24-h urinary salt excretion from overnight urine samples. Methods: Twelve young, healthy female volunteers consumed test meals from days 1 to 14 and estimated urinary salt excretion on days 2–15 by using a self-monitoring device. The salt content of the test meals was as follows: 10 g (days 1–5), 6 g (days 6–8), 13 g (days 9–11), 6 g (day 12), 13 g (day 13), and 6 g (day 14). Results: The average 24-h urinary salt excretion (the ratio of urinary salt excretion to salt intake of the previous day) estimated from the overnight urine samples was as follows: 8.01±1.15 g (0.73±0.11) on days 2-6, 5.86±0.85 g (1.01±0.15) on days 7-9, 9.69±1.64 g (0.74±0.13) on days 1012, 6.51±1.56 g (1.03±0.25) on day 13, 8.60±3.25 g (0.71±0.14) on day 14, and 6.28±1.31 (1.05±0.22) on day 15. Thus, the salt excretion/salt intake ratio was approximately 0.8 during the high-salt phase and 1.0 during the low-salt phase. Conclusion: The estimation of 24-h urinary salt excretion from overnight urine samples by using a self-monitoring device is a reasonably valid method in this young and healthy female population for detecting daily changes in salt intake.