Attenuated Associations between Increasing BMI and Unfavorable Lipid Profiles in Chinese Buddhist Vegetarians

肥胖往往伴随着血脂升高和心血管疾病的风险增加。在肥胖和高脂血症高发的西方国家，素食已经被证实能够给患者带来益处。本文着重探讨低心血管风险的中国南方人的BMI和血脂代谢水平，以及其与心血管风险预测值的关系。本研究共纳入170名素食者和126普通饮食的正常男性，运用交互作用多元回归等统计方法探讨BMI和心血管多种危险因素的关系。结果显示，素食组的BMI、血压、總胆固醇、LDL胆固醇、HDL胆固醇、總胆固醇／HDL胆固醇、三酸甘油酯、载脂蛋白B、载脂蛋白A-I，以及心血管风险预测值等均明显比普通饮食组較低。不管是素食组或者普通饮食组，随着BMI升高，研究对象的血脂水平和心血管风险预测值均呈现升高的趋势。然而，相比于普通饮食组，素食组BMI与血脂水平和心血管风险预测值的交互作用明显下降。结论：素食不仅降低研究对象的BMI水平，同时能够改善BMI相关的血脂紊乱和心血管风险增加。

關鍵字

素食； BMI ；血脂；血脂蛋白；中国人群

並列摘要

Obesity is related to hyperlipidemia and risk of cardiovascular disease. Health benefits of vegetarian diets have well-documented in the Western countries where both obesity and hyperlipidemia were prevalent. We studied the association between BMI and various lipid/lipoprotein measures, as well as between BMI and predicted coronary heart disease probability in lean, low risk populations in Southern China. The study included 170 Buddhist monks (vegetarians) and 126 omnivore men. Interaction between BMI and vegetarian status was tested in the multivariable regression analysis adjusting for age, education, smoking, alcohol drinking, and physical activity. Compared with omnivores, vegetarians had significantly lower mean BMI, blood pressures, total cholesterol, low density lipoprotein cholesterol, high density lipoprotein cholesterol, total cholesterol to high density lipoprotein ratio, triglycerides, apolipoprotein B and A-I, as well as lower predicted probability of coronary heart disease. Higher BMI was associated with unfavorable lipid/lipoprotein profile and predicted probability of coronary heart disease in both vegetarians and omnivores. However, the associations were significantly diminished in Buddhist vegetarians. Conclusions: Vegetarian diets not only lower BMI, but also attenuate the BMI-related increases of atherogenic lipid/lipoprotein and the probability of coronary heart disease.

並列關鍵字

vegetarian diet ； BMI ； lipid ； lipoprotein ； Chinese

參考文獻

Lee Y, Krawinkel M. Body composition and nutrient intake of Buddhist vegetarians. Asia Pac J Clin Nutr. 2009;18:265- 71.

Key TJ, Davey GK, Appleby PN. Health benefits of a vegetarian diet. Proc Nutr Soc. 1999;58:271-5.

Dwyer JT. Health aspects of vegetarian diets. Am J Clin Nutr. 1988;48(3 Suppl):712-38.

Key TJ, Fraser GE, Thorogood M, Appleby PN, Beral V, Reeves G et al. Mortality in vegetarians and nonvegetarians: detailed findings from a collaborative analysis of 5 prospective studies. Am J Clin Nutr. 1999;70(3 Suppl): 516S-24S.

Chen CW, Lin YL, Lin TK, Lin CT, Chen BC, Lin CL. Total cardiovascular risk profile of Taiwanese vegetarians. Eur J Clin Nutr. 2008;62:138-44.

國際替代計量

Attenuated Associations between Increasing BMI and Unfavorable Lipid Profiles in Chinese Buddhist Vegetarians

全文下載

主題瀏覽