Distinct Utility of Ga-68 PSMA-11 PET/CT and F-18 FDG PET/CT in a Patient Diagnosed With Double Cancer

鎵68-特異性攝護腺膜抗原正子斷層掃描與氟18-去氧葡萄糖正子斷層掃描在雙重癌症患者的具體運用

張思瀚(Szu-Han Chang) ； 蔡席晨(Hsi-Chen Tsai) ； 吳桂芳(Kwai-Fong Ng) ； 馮思中(See-Tong Pang) ； 曾敬仁(Jing-Ren Tseng)

《核子醫學暨分子影像雜誌》 33卷1期 (2020/03) Pp. 50-55

https://doi.org/10.6332/ANMMI.202003_33(1).0007

摘要

We present the case of an 81-year-old man with a newly diagnosed prostate cancer who showed different findings on two distinct positron emission tomography/ computed tomography (PET/CT) imaging modalities. Specifically, Ga-68 prostate-specific membrane antigen (PSMA)-11 PET/CT identified three foci of increased tracer uptake in the prostate, liver, and left upper lobe of lung, whereas an abnormal uptake in the prostate and left upper lobe of lung was evident on F18-FDG PET/CT. Subsequent lung lobectomy revealed the presence of a well-differentiated adenocarcinoma of pulmonary origin. Our case demonstrates that F-18 FDG PET/CT can provide complementary diagnostic information in a complex clinical scenario like double cancer.

關鍵字

FDG ； lung cancer ； PET ； prostate cancer ； PSMA

並列摘要

一個新診斷為攝護腺癌的81歲男子接受Ga-68 prostate specific membrane antigen-11 positron emission tomography/computed tomography（PET/CT）檢查，顯示3處示蹤劑攝取增加的病灶，分別位於攝護腺、肝和左上肺葉，同時F-18 fludeoxyglucose（FDG）PET/CT顯示攝護腺及左上肺葉病灶攝取增加，隨後的肺葉切除術診斷為肺部原發分化良好腺癌。此案例顯示F-18 FDG PET/CT的結果可在如雙重癌症的臨床情境中提供輔助。

並列關鍵字

特異性攝護腺膜抗原 ； 氟化去氧葡萄糖 ； 正子斷層造影 ； 攝護腺癌 ； 肺癌