Short Communication: Malignant Catarrhal Fever Associated with Caprine Herpesvirus-2 Infection in Captive Formosan Sika Deer (Cervus Nippon Taiouanus) in Taiwan

簡訊：台灣圈飼梅花鹿感染山羊第二型疱疹病毒恶性卡他熟

陳世平(Shih-Ping Chen) ； 李明昌(Ming-Chung Lee) ； 孫豫芬(Yu-Fen Sun) ； 陳啟銘(Chi-Min Chen) ； 楊平政(Ping-Chen Yang) ； 鄭益谦(Ivan-Chen Cheng)

《臺灣獸醫學雜誌》 33卷3&4期 (2007/12) Pp. 162-166

https://doi.org/10.7009/TVJ.200712.0162

摘要

本篇報告為首次以聚合酶鏈反應及基因定序診斷台灣本地梅花鹿因感染山羊第二型庖疹病毒所引發之慢性惡性卡他熱臨床症狀與病理特徵。在2002年九月到2003年元月間，圈養在一起的鹿群中有12頭死於逐漸消瘦，另外兩頭無可見病狀。剖檢肉眼病變有心、腸繫膜淋巴結與腎的明顯動脈硬化；12頭動物都有嚴重淋巴球性血管炎，伴隨血管內膜增生、與慢性惡性卡他熱吻合的顯微病理病變。感染鹿與圈飼於同舍不同欄的山羊血清中，均可檢出惡性卡他熱抗體，這些外表健康的山羊於山羊第二型庖疹病毒的聚合酶鏈反應檢測均呈陽性，但圈飼於同舍不同欄的牛隻檢測結果則呈陰性。推測本案例中無臨床症狀、但為山羊第二型疱疹病毒帶原者的健康山羊是造成鹿隻感染發病的病毒來源。

關鍵字

惡性卡他熱 ； 山羊第二型疱疹病毒 ； 聚合酶鏈反應

並列摘要

Caprine herpesvirus-2 (CpHV-2) infection in Formosan sika deer (Cervus nippon toiouanus) with clinical signs and pathological changes of chronic malignant catarrhal fever (MCF) detected by polymerase chain reaction (PCR) and sequencing in Taiwan is reported here. During the period of September 2002 and January 2003, 12 Formosan sika deer died with progressive weight loss; while 2 other deer in the same captive herd were subclinically infected. At necropsy, gross lesions were characterized by marked arteriosclerosis in the heart, mesentery, and kidneys were noted. Microscopically, all 12 animals had severe lymphocytic vasculitis with intimal hyperplasia that were consistent with the lesions of chronic MCF. Antibody to MCF virus was detected in sera collected from all deer and goats housing in the same barn. Clinically normal goats, but not cattle, in the same barn were also PCR positive for CpHV-2. Subclinically CpHV-2-infected goats were considered to be the source of infection in this incidence.

並列關鍵字

Malignant catarrhal fever MCF ； Caprine herpesvirus-2 CpHV-2 ； Polymerase chain reaction