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The Contents of Parishin, Parishin B and Parishin C in Traditional Decoctions and Commercial Extracts of Gastrodiae Rhizoma

並列摘要


The contents of parishin, parishin B and parishin C in six traditional decoctions and six commercial extracts of Gastrodiae Rhizoma were analyzed by high performance liquid chromatography. Separation and quantitation were performed on a Cosmosil 5C18-AR column by gradient elution with varied ratios of 0.1 % (v/v) phosphoric acid: methanol as the mobile phase at a flow rate of 1.0 mL/min and detection at 222 nm. Sulfamethoxypyridazine was used as the internal standard. The contents of parishin, parishin B and parishin C in traditional decoctions of Gastrodiae Rhizoma were 2.7±0.5 mg/g, 2.3 ± 0.2 mg/g and 1.6 ± 0.3 mg/g, whereas commercial extracts contained 6.9± 0.9 mg/g, 2.7± 0.3 mg/g and 1.6± 0.1 mg/g, respectively. Based on our results, the maximum daily doses of parishin, parishin Band parishin C in traditional decoctions of Gastrodiae Rhizoma were 24.1± 4.5 mg, 20.4± 2.0 mg and 14.4± 2.6 mg compared to 15.6± 1.4 mg, 6.5± 1.1 mg and 4.1± 0.7 mg in commercial extracts, respectively. The daily dose of parishin, parishin Band parishin C were higher in traditional decoctions than in commercial extracts.

並列關鍵字

Gastrodia elata Parishin Parishin B Parishin C

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