- 期刊
Pituitary Oncocytoma: Three Cases Report
腦垂腦瘤細胞瘤：三病例報告
摘要
腦垂腦瘤細胞瘤並非罕見，高雄醫學院腦神經外科在102個腦垂腺腫中共經鎮歷3例腦垂腦瘤細胞瘤，包括男性2例，女性1例，平均年齡62.7歲，以頭痛、視覺障礙及全身倦怠為其主訴。3病例均接受經蝶竇腦垂腺腫摘除術移除腺腫，而以免疫細胞化學染色法及電子顯微鏡檢查確定診斷。其超顯微構造呈現發育欠坐的胞器及細胞質內的大量粒腺體聚集。術後追蹤，病人的症狀均獲顯著改善。
關鍵字
無資料並列摘要
Three out of 102 pituitary adenoma patients, including 2 males and one female, had their pituitary tumors diagnosed as ”oncocytomas” and underwent transsphenoidal adenomectomy. The tumors were confirmed as ”pituitary oncocytomas” by both immunohistochemical staining and electron microscopy. They had poorly developed subcellular organelles and were markedly hyperplastic and pleomorphic, with swollen mitochondria in the cytoplasm and scattered secretory granules along the cell membranes. Postoperative follow-up revealed that visual acuity gradually improved in all the patients and no tumor recurrence was found. The accurate pre-operative diagnosis of pituitary oncocytomas relies on endocrinological, neuroradiological clinical evaluation, and the management of this dis-ease must be surgery with postoperative radiotherapy
延伸閱讀
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