With the characteristics of geography and topography, the impacts of natural disasters like typhoon and earthquake, the environmental vulnerability, Taiwan is facing the steep challenge to protect the speedy development from the increased frequency and scale of natural hazard. Beyond the natural incidents, the man-made accidents and epidemic disease have shown the potential risk. On the eve of governmental reorganization, the necessary re-examination of jurisdiction and unavoidable adjustment of administrative level on, would further improve the capacity and capability on disaster prevention management system. The article would present the current status and historical development in Taiwan, US and Japan and provide the preliminary suggestions for future innovation.