Drug abuse has long been recognized as one of the major problems facing the world today. As a result, countries all over the world have taken tough measures to curb this problem. Generally speaking, the strategies adopted share the common aim of attempting to disrupt the supply of drugs into their respective countries while at the same time reducing the demand for such illicit drugs back home. The difference between these strategies lies in the methods used, the criminal penalties incurred, as well as the effect drugs have on public health and security. The success of such policies will also affect any changes a country might make to its own drug policy. This article will focus on the representative case studies of the United States, Thailand, Japan, Australia and the Netherlands, introducing the drug policy as well as the current trends and developments in this arena for each of these countries and the European Union. It is hoped that this article will serve as a useful resource as our country seeks to amend its own drug policy.