Spiral tube convection heat exchanger has the advantages of compact structure, self-cleaning, high heat transfer efficiency and low cost, so it is widely used in chemical, power, power and other industries. In this paper, a spiral tube heat exchanger is modeled by UG software, and then the tetrahedral mesh is divided by ICEM software. FLUENT is used to simulate the convection heat transfer performance of spiral tube heat exchanger under different cooling air flow conditions. The air flow rule and heat transfer coefficient in the spiral tube heat exchanger are studied and analyzed. This paper provides theoretical basis and data support for the calculation and design of the helical tube heat exchanger, and has a certain application value.