肝細胞癌之上顎牙齦轉移－病例報告

根據行政院衛生署統計，癌症爲台灣十大死因之首，而肝癌在男性爲第一位，在女性則爲第二位。肝癌轉移至口腔的病例十分罕見，目前僅有少數的病例被文獻所記載，因此對該疾病的流行病學、治療及預後仍不是相當清楚。本文報告一位45歲男性患者，西元2007年8月被診斷罹患肝癌後，接受肝右葉切除手術，並因殘餘腫瘤接受肝動脈栓塞治療。西元2007年12月因在它院拔除左側上顎第三大臼齒，術後傷口疼痛，於本科求診。檢查發現上顎左側後牙區有一容易出血之腫塊，大小約2.8×2.5×2.0公分，經病理切片檢查，確定診斷爲肝癌之上顎牙齦轉移，之後病患接受口腔轉移部位之放射線治療。在確定口腔部位轉移的8個月後，病患死於腫瘤肺臟轉移併發惡性肺積水。

關鍵字

肝細胞癌；腫瘤轉移；口腔

並列摘要

According to the statistics provided by the Department of Health, cancer is the leading cause of death in Taiwan. Hepatic cancer ranks first among the causes of death in men while it ranks second among that in women. However, oral metastasis of hepatic cancer is extremely rare. Due to the low number of reported case, the epidemiology, treatment and prevention of this clinical predicament remains poorly understood. This case report presents a 45-year-old male, who was diagnosed with hepatocellular carcinoma in August 2007. He underwent right hepatic lobectomy as well as transcatheter arterial embolization for treatment of residual tumor. In December 2007, the patient had his left maxillary third molar extracted and came to our department after experiencing post-operative pain. Intraoral examination revealed a mass, measured about 2.8×2.5×2.0 cm^3, at the upper left posterior area that bled easily when provoked. A biopsy of the lesion confirmed gingival metastasis of the hepatic tumor. As a result, the patient received radiotherapy to the metastatic site. However, the patient expired due to lung metastasis complicated with malignant pleural effusion eight months after he was diagnosed with gingival metastasis of the cancer.

並列關鍵字

hepatocellular carcinoma ； metastasis ； oral cavity

國際替代計量

肝細胞癌之上顎牙齦轉移－病例報告

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