This report describes a middle-aged woman with a tumor of the brain. The patient suffered from postoperative hemiplegia, encountering physical and psychological problems as a result. The information was obtained by interview and observation, finding that there were four major problems. (1) altered cerebral tissue perfusion; (2) impaired physical mobility; (3) powerlessness; and (4) altered family processes. According to the patient's needs, the author worked with the medical team and drafted rehabilitation plans with the patient and her family. They were encouraged to participate actively in physical activities and functional training. Nurses provided positive support for strengthening of psychological adjustment to overcome the crisis of powerlessness; furthermore, assistance was given to the family in looking forward to creating interactive care as well as providing rental devices and respite care services. We expect that the family would have enough capacity to take care of the patient after discharge.