- 期刊
放射線引起之外耳道軟骨肉瘤－病例報告
Radiation-induced Chondrosarcoma of the External Ear Canal – Case Report
並列摘要
Radiation therapy is the mainstay treatment for nasopharyngeal carcinoma (NPC). Nevertheless, the incidence of radiation-induced sarcoma (RIS) remains low in patients with NPC, and radiation-induced chondrosarcoma has not been reported. Herein, we report the case of a 45-year-old man who developed radiation-induced chondrosarcoma in the cartilaginous ear canal eight years after receiving radiation therapy for an NPC. On admis-sion, he complained of tenderness and swelling in the left ear canal. Physi-cal examination revealed a smooth bulging mass originating from the carti-laginous ear canal. Lateral temporal bone resection was performed and pathological examination revealed chondrosarcoma. The post-operative course was smooth and no evidence of tumor recurrence was found during the follow-up of 8 months. The location of the tumor, the interval after previous irradiation, and the histological findings were all consistent with a diagnosis of RIS. To our knowledge, this is the first reported case of radia-tion-induced chondrosarcoma. Because early diagnosis of RIS offers the only chance for cure, early work-up of any fresh pain and swelling in an irradiated field is vital.
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