魚油增補對運動引發氧化壓力的探討

Effects of High-Intensity Exercise and Fish Oil-Induced Oxidative Stress

姚承義(Chern-Yu Yau) ； 謝伸裕(Sandy Hsieh) ； 沈淑貞(Shu-Chen Shen)

《運動生理暨體能學報》 2輯 (2005/04) Pp. 67-78

https://doi.org/10.6127/JEPF.2005.02.06

摘要

Exercise may induce higher oxygen free radicals. Fish oil belong to ω-3 PUFA series that can decrease TG and influence plasma blood lipids. Howerever, some evidence suggests it may increases the lipid peroxidation in the cell. Purpose: To investigates the effects of high-intensity exercise with fish oil supplementation on the antioxidant defense system. Methods: Thirty-three (33) healthy males (20.3±1.4 yrs; 64.3±7.9 kg) were randomly assigned into four groups, which were given a combinations of dietary fish oil (9 g /day), exercise (intensity 85~90%HRmax reserve), and placebos. The experiment lasted for 4 weeks. Venous samples were obtained prior to exercise and within 5 min after exercise. Four venous blood samples were also taken during the four-week period. Blood from all groups was analyzed for SOD, GSH-Px, t-GSH, TAA, MDA. A Generalized Estimating Equations (G.E.E.) method was used for data analysis. Results: The fish oil groups SOD activity significantly increased 11.27 kU/g-HB (p＜.05) and decrease in GSH-Px levels, but not appear in the exercise groups. Following exercise in the fish oil group, t-GSH increased significantly 16.07% (p＜.05). MDA increased significantly after exercise in both exercise-alone and exercise/fish oil groups 0.12 and 0.27 mmole/ml (p＜.05) respectively. Conclusions: exercise and fish oil can cause an increase in oxidative stress separately. Also, these two effects are additive.

關鍵字

激烈運動 ； 魚油 ； 氧化性傷害

並列摘要

Exercise may induce higher oxygen free radicals. Fish oil belong to ω-3 PUFA series that can decrease TG and influence plasma blood lipids. Howerever, some evidence suggests it may increases the lipid peroxidation in the cell. Purpose: To investigates the effects of high-intensity exercise with fish oil supplementation on the antioxidant defense system. Methods: Thirty-three (33) healthy males (20.3±1.4 yrs; 64.3±7.9 kg) were randomly assigned into four groups, which were given a combinations of dietary fish oil (9 g /day), exercise (intensity 85~90%HRmax reserve), and placebos. The experiment lasted for 4 weeks. Venous samples were obtained prior to exercise and within 5 min after exercise. Four venous blood samples were also taken during the four-week period. Blood from all groups was analyzed for SOD, GSH-Px, t-GSH, TAA, MDA. A Generalized Estimating Equations (G.E.E.) method was used for data analysis. Results: The fish oil groups SOD activity significantly increased 11.27 kU/g-HB (p＜.05) and decrease in GSH-Px levels, but not appear in the exercise groups. Following exercise in the fish oil group, t-GSH increased significantly 16.07% (p＜.05). MDA increased significantly after exercise in both exercise-alone and exercise/fish oil groups 0.12 and 0.27 mmole/ml (p＜.05) respectively. Conclusions: exercise and fish oil can cause an increase in oxidative stress separately. Also, these two effects are additive.

並列關鍵字

High-intensity exercise ； Fish oil ； Oxidative stress

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