白蝦(Litopeneaus vannamei; 5±0.6 g)注射20μg shrimp^(-1)小海帶(Endarachne binghamiae)萃取物,可顯著提高對溶藻弧菌(Vibrio alginolyticus)感染之存活率。另外,以脂多醣與β-1,3-葡聚醣結合蛋白及原酚氧化酵素、細胞黏附蛋白、穀胱甘肽過氧化酶、溶菌酶、絲氨酸蛋白酶基因表現為免疫指標,評估白蝦後期幼苗餵飼小海帶萃取物(0, 5, 10 gl^(-1))滋養的豐年蝦(Arremia)無節幼蟲4小時後之免疫狀態。結果顯示,白蝦餵飼小海帶萃取物滋養之豐年蝦無節幼蟲144小時後,脂多醣與β-7,3-葡聚醣結合蛋白及細胞黏附蛋白、穀胱甘肽過氧化酶、溶菌酶之基因表現量明顯提升。因此,小海帶萃取物可誘發白蝦幼苗之免疫調節,進而增強其免疫能力及對溶藻弧菌感染之抵抗力。
White shrimp, Litopenaeus vannamei (5±0.6 g), which received the extract from the brown alga, Endarachne binghamiae (EB), at 20 μg shrimp^(-1) showed a significantly increased survival rate after challenge with Vibrio alginolyticus. Lipopolysaccharide- and β-1, 3-glucan-binding protein (LGBP), prophenoloxidase (proPO), peroxinectin (PE), glutathione peroxidase (GPX), lysozyme (LYS), and serine proteinase (SP) gene expression were used as immune indicators to evaluate the state of immunity of white shrimp postlarvae (PL10) after having been individually fed Artemia nauplii which had been exposed to 0, 5, and 10 gl^(-1) of the extract of EB for 4 h. Results showed that the expressions of LGBP, PE, GPX, and LYS were significantly elevated in shrimp postlarvae fed the extract of EB-enriched Artemia nauplii after 144 h. It was concluded that administration of the extract of EB induces immune modulation, enhances the immune ability of L. vannamei, and increase its resistance to V. alginolyticus infection.